Survival curves of laryngeal squamous cell carcinoma determined using the Kaplan-Meier estimator method and the log-rank test. Overall survival curves are shown for (A) Wnt5a+ (green line, 1) and Wnt5a− (blue line, 0), patients in the high-expression group (Wnt5a+) had significantly poorer prognosis compared with those in the low-expression group (Wnt5a; P=0.020, log-rank test); (B) Ror2+ (green line, 1) and Ror2− (blue line, 0), patients in the high-expression group (Ror2+) had significantly poorer prognosis compared with those in the low-expression group (Ror2; P=0.001, log-rank test); and (C) Wnt5a+/Ror2+ (red line, 2), Wnt5a+/Ror2− or Wnt5a−/Ror2+ (green line, 1) and Wnt5a−/Ror2− (blue line, 0), patients in the high Wnt5a and high Ror2 expression group (Wnt5a+/Ror2+) had significantly poorer prognosis compared with both those in the high Wnt5a or high Ror2 expression group (Wnt5a+/Ror2− or Wnt5a−/Ror2+) and those in the low-expression group (Wnt5a−/Ror2; P=0.001, log-rank test). Wnt5a, Wnt family member 5a; Ror2, receptor tyrosine kinase-like orphan receptor 2.