Figure 3.

Expression levels of miR-452 in breast cancer cell lines detected by RT-qPCR. (A) The relative expression of miR-452 was downregulated in breast cancer cell lines compared with the normal breast epithelial cell line, MCF-10A. (B) The transfection efficiency of an miR-452 mimic was assessed by comparing the detected miR-452 levels of mimic-transfected cells, with miR-NC-transfected cells, using RT-qPCR. Data are presented as the mean ± standard deviation. *P<0.05 vs. MCF-10A or miR-NC. miR-452, microRNA-452; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; miR-NC, negative control microRNA.