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. 2017 Jun 16;14(2):2053–2058. doi: 10.3892/ol.2017.6397

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — (A) Representative images of TXNIP immunohistochemical staining by treatment with DAB chromogen and hematoxylin in (A-a) WHO grade I gliomas, (A-b) WHO grade II gliomas, (A-c) WHO grade III gliomas and (A-d) WHO grade IV gliomas. The expression level of TXNIP was significantly decreased in higher grade tumors (P<0.05). (B) The relative expression of TXNIP mRNA detected by reverse transcription-quantitative polymerase chain reaction. The expression level of TXNIP mRNA was significantly decreased in higher grade tumors. (C) The association of TXNIP expression with the overall survival of glioma patients. WHO, World Health Organization; TXNIP, thioredoxin-interacting protein.