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. 2017 Jun 20;14(2):2141–2146. doi: 10.3892/ol.2017.6433

Figure 3.

Figure 3.

HCV-E2 stimulation increases expression of miR-490 in MCs, MC-derived exosomes, and recipient HCC cells. (A) The levels of miR-490 in the MCs with and without HCV-E2 treatment, and the exosomes from them detected by qRT-PCR (*P<0.05). (B) The levels of miR-490 in HCC cells after 24 h incubation with exosomes from the MCs with and without HCV-E2 treatment detected by qRT-PCR (*P<0.05). (C) EGFR expression and phosphorylation of ERK1/2 in HCC cells after 24 h incubation with exosomes from the MCs with and without HCV-E2 treatment detected by western blot analysis. HCV-E2, hepatitis C virus E2 envelope glycoprotein; MC, mast cell; HCC, hepatocellular carcinoma. **P<0.01.