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. 2017 Jun 20;14(2):2141–2146. doi: 10.3892/ol.2017.6433

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Copyright: © Xiong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — miR-490 in MC-derived exosomes regulated HCC cell migration. (A) Expression of miR-490 in miR-490 antagomir pre-transfected MCs with or without HCV-E2 treatment was detected by qRT-PCR (*P<0.05). (B) The expression level of miR-490 in MCs pre-transfected with antagomiR-490 and the MCs-derived exosomes detected by qRT-PCR. (C) The expression of miR-490 in HCC cells after incubation with exosomes from MCs pre-transfected with antagomiR-490 was detected by qRT-PCR (*P<0.05). (D) HCC cells were co-cultured with antagomiR-490 or exosomes from the MCs pre-transfected with antagomiR-490. Transwell assay was used to detect the migration of cells in each group (*P<0.05). MC, mast cell; HCC, hepatocellular carcinoma; HCV-E2, hepatitis C virus E2 envelope glycoprotein. **P<0.01; ***P<0.001.