Table II.

Univariate and multivariate analyses of association between clinicopathological factors and progression-free survival in patients with non-muscle-invasive bladder cancer.

	Univariate analysis		Multivariate analysis
Parameters	5-year recurrence-free rate, %	P-valuea	HR	95% CI	P-valueb
Sex		0.926			0.498
Male	26.4		1
Female	26.6		1.24	0.67–2.30
Age		0.313			0.168
<60	40.8		1
≥60	20.6		1.51	0.84–2.69
Tumor diameter, cm		0.359			0.114
≤3	28.8		1
>3	25.5		1.55	0.90–2.66
Tumor number		0.042			0.008
Single	34.9		1
Multiple	14.6		2.12	1.22–3.68
Tumor grade		0.080			0.029
Low grade	28.6		1
High grade	13.2		2.15	1.08–4.29
TRAF6 expression		0.016			0.011
Low	33.9		1
High	18.7		2.04	1.18–3.53

^aMeans calculated by Kaplan-Meier analysis and the log-rank test.

^bMeans calculated using the Cox-regression model. CI, confidence interval; HR, hazard ratio; TRAF6, TNF receptor-associated factor 6.