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. 2017 Jun 21;14(2):2261–2267. doi: 10.3892/ol.2017.6439

Figure 2.

Figure 2.

MTT and colony formation assays. (A) Growth curve comparing MDA-MB-231 cells treated with miR-340 mimics vs. mimics NC. (B) Growth curve comparing MDA-MB-231 cells treated with miR-340 inhibitors vs. inhibitor NC. Post-transfection time is shown on the x-axis. Cells transfected with miR-340 exhibited inhibited proliferation, whereas miR-340 suppression markedly increased cell proliferation, when compared with that of the control. (C) Colony formation assays showing the effect of miR-340 mimics vs. mimic NC on MDA-MB-231 cell growth. (D) Colony formation assays showing the effect of miR-340 inhibitors vs. inhibitor NC on MDA-MB-231 cell growth. miR-340 mimics significantly suppressed cell proliferation when compared with that of NC mimics. P<0.05 for miR-340 mimics vs. mimic NC; miR-340 inhibitors vs. inhibitor NC. NC, negative control; miR, microRNA; OD, optical density.