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. 2017 Jun 9;76(7):1199–1206. doi: 10.1136/annrheumdis-2016-210373

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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Genome-wide association study design, showing primary and secondary analyses. svns, superior joint space narrowing versus non-superior; amvnam, axial/medial joint space narrowing versus non-axial/medial; hvnh, hypertrophic bone response versus non-hypertrophic; avna, atrophic bone response versus non-atrophic; svcon, superior joint space narrowing versus population-based controls; amvcon, axial/medial joint space narrowing versus population-based controls; hvcon, hypertrophic bone response versus population-based controls; avcon, atrophic bone response versus population-based controls; hipvcon, hip osteoarthritis (OA) versus population-based controls.