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. 2017 Jun 9;76(7):1228–1236. doi: 10.1136/annrheumdis-2016-210424

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(A–D) IHC for CD31⁺ vessels on ST of patients with rheumatoid arthritis (RA) in remission, in low disease activity (LDA) and in high/moderate disease. (A) Example photos of CD31 (brown) staining of ST from patient with high/moderate RA (a, b) (magnification 20×); corresponding ultrasound assessment (US) picture with PD scale (PD score=2) of the knee used for ST biopsy is shown. (B) Example photos of CD31 (brown) staining of ST from patient with RA in LDA (a, b) (magnification 20×); corresponding US picture with PD scale (PD score=0) of the knee used for ST biopsy is shown. (C) Example photos of CD31 (brown) staining of ST from patient with RA in remission (a, b) (magnification 20×); corresponding US picture with PD scale (PD score=0) of the knee used for ST biopsy is shown. (D) IHC score for CD31⁺ vessels in ST of enrolled cohorts; high/moderate versus LDA in patients with RA, **p<0.001; high/moderate versus remission in patients with RA, **p<0.001; LDA versus remission in patients with RA, p=0.57.