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. Author manuscript; available in PMC: 2017 Jul 27.
Published in final edited form as: Kidney Int. 2016 Sep 22;91(1):86–95. doi: 10.1016/j.kint.2016.07.039

Figure 1. Effects of chronic kidney disease (CKD) and RAP-011 on osteoclasts and bone resorption.

Figure 1

CKD stimulated osteoclast number (Oc.N.) per bone length (BL) and osteoclast surface per bone surface (Oc.S./BS) along with eroded surface per bone surface (ES/BS) in the distal femoral metaphysis. RAP-011 treatment reversed the effects of CKD. **P < 0.01 for comparisons between sham and chronic kidney disease mice treated with vehicle (CKD V) and between CKD V and CKD R. CKD R, CKD+RAP-011; WT, wild type.