. Author manuscript; available in PMC: 2017 Jul 27.

Published in final edited form as: Kidney Int. 2016 Sep 22;91(1):86–95. doi: 10.1016/j.kint.2016.07.039

Table 2.

Serum biochemical parameters in the various groups of animals

Parameter	Wild type	Sham	CKD V	CKD R
Mouse strain	C57/BJ6	ldlr−/−	ldlr−/−	ldlr−/−
Diet	Chow	High fat	High fat	High fat
Surgery	None	Sham	CKD	CKD
Weeks postnatal	28	28	28	28
Treatment	None	None	Vehicle	RAP-011
No.	12	15	14	15
BUN (mg/dl)	24.0 ± 4.6	20.6 ± 3.7	37.7 ± 7.6^a	36.5 ± 5.8^a
Ca (mg/di)	8.3 ± 1.8	8.9 ± 0.9	9.4 ± 0.8	8.8 ± 0.3
Phosphorus (mg/di)	8.9 ± 0.2	7.9 ± 2.3	11.0 ± 1.6^a	11.8 ± 1.2^a

BUN, blood urea nitrogen; Ca, calcium; CKD R, chronic kidney disease receptor; CKD V, chronic kidney disease mice treated with vehicle.

P < 0.05, CKD V and CKD R compared with sham. Inulin clearances in the mice were reported in Agapova et al.¹⁶