Table 3.
Genotypic distribution, relative allele frequencies, and odds ratio (OR) for the CYP2C19∗2 variant in Chilean patients with and without restenosis.
| Polymorphism rs4244285 |
Genotypes | Allele frequency | |||
|---|---|---|---|---|---|
| GG | AG | AA | G | A | |
| Cases, n = 77 | 69 (89.6%) | 8 (10.4%) | 0 (0.0%) | 0.95 (146) | 0.05 (8) |
| Controls, n = 86 | 68 (79.0%) | 17 (19.8%) | 1 (1.2%) | 0.90 (153) | 0.10 (19) |
| p value | 0.150 (χ2 = 3.76) | 0.055 (χ2 = 3.66) | |||
| Odds ratio | 0.44 (95% CI: 0.19–1.04); p = 0.06 | ||||
n: number of individuals. Genotype frequency values given as percentage. p value calculated by chi-square. CI: confidence interval. HWE (cases: χ2 = 0.23; p = 0.63; controls: χ2 = 0.002; p = 0.95).