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. 2017 Jul 27;18:140. doi: 10.1186/s13059-017-1267-2

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Single cell validation of ReMixT results for 12 breakpoints in 294 cells from 4 HGS Ovarian tumour samples: Omentum 1 (Om1), Right Ovary 1 and 2 (ROv1 and ROv2), and Left Ovary 1 (LOv1). (a) Breakpoint (x-axis) by cell (y-axis) presence (dark blue) / absence (light blue) with cells annotated by sample of origin and clone as inferred by the Single Cell Genotyper. (b) Approximate anatomic location of the 4 tumour samples. (c) F-measure, precision and recall for ReMixT calls of breakpoint presence and subclonality