Table 1.

General characteristics and factors associated with ESA prescription: univariate analysis (Student T-test test or chi square test as appropriate, n = 240 patients)

	Total population (n = 240)	Patients without ESA (n = 71)	Patients with ESA (n = 169)	p-value
Age (years)	67.6 ± 16.0	68.6 ± 14.8	67.3 ± 16.6	0.56
Male gender	55.4%	62.0%	52.7%	0.19
Time on dialysis (months)	82 ± 121	80 ± 89	83 ± 133	0.87
Diabetes mellitus	42.5%	43.7%	42.0%	0.81
Dry weight (kg)	69.6 ± 14.9	71.4 ± 15.6	68.9 ± 14.6	0.23
ADPKD	4.6%	4.2%	4.7%	1.00
White cell count (G/L)	7.01 ± 4.62	6.55 ± 2.05	7.21 ± 5.34	0.31
Lymphocytes (G/L)	1.28 ± 0.58	1.34 ± 0.62	1.25 ± 0.57	0.27
Hemoglobin (g/dL)	10.8 ± 1.2	11.4 ± 1.1	10.6 ± 1.2	<0.001
MCV (fl)	94 ± 8	93 ± 6	95 ± 8	0.33
Platelet count (G/L)	203 ± 79	187 ± 70	209 ± 82	0.06
TSAT (%)	25.5 ± 13.5	31.1 ± 16.3	23.1 ± 11.5	<0.001
Ferritin (ng/mL)	530 ± 520	577 ± 640	510 ± 461	0.36
Albumin (g/L)	37.7 ± 5.3	37.9 ± 4.8	37.6 ± 5.5	0.65
β2 microglobulin (mg/L)	26.6 ± 7.4	27.4 ± 7.9	26.4 ± 7.1	0.40
Parathormone (pg/mL)	256 ± 318	263 ± 313	252 ± 119	0.82
Predialysis creatinine (μmol/L)	732 ± 253	748 ± 273	725 ± 244	0.52
Predialysis urea (mmol/L)	20.7 ± 6.6	20.4 ± 5.9	20.8 ± 6.8	0.64
C-reactive protein (mg/L)	20.0 ± 43.5	16.6 ± 37.8	21.4 ± 45.7	0.44
IAA (μmol/L)	4.73 ± 4.79	4.79 ± 5.06	4.71 ± 4.69	0.91
IS (μmol/L)	93.3 ± 51.5	91.1 ± 53.0	94.2 ± 51.0	0.67
PCS(μmol/L)	158 ± 99	165 ± 99	154 ± 99	0.44
ESA dose (μg/w)	-	-	53.9 ± 50.0	-
IV iron medication (%)	61.7%	52.1%	65.7%	0.04
Iron dose (mg/mo)	232 ± 267	173 ± 200	257 ± 288	0.03
Vascular access
Native AV fistula	63.3%	54.9%	66.9%	0.17
AV graft	16.7%	18.3%	16.0%
Catheter	20.0%	26.8%	17.2%
HDF (%)	41.7%	53.5%	36.7%	0.02
Kt/V	1.51 ± 0.31	1.51 ± 0.26	1.51 ± 0.32	0.98

Results are provided as mean ± SD or percentages. ESA erythropoiesis stimulating agent, ADPKD autosomal dominant polycystic disease, MCV mean corpuscular volume, IS indoxylsulfate, IAA indole-3-acetic acid, PCS paracresyl-sulfate, AV arteriovenous, HDF hemodiafiltration