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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Amyotroph Lateral Scler Frontotemporal Degener. 2017 Mar 29;18(5-6):358–366. doi: 10.1080/21678421.2017.1303515

Table 2.

Summary of included acoustic and kinematic subsystem measures

Speech subsystem Measure Experimental Task Procedures
Respiratory Percent pause time (%) (PPT) Reading of Bamboo passage Pauses > 300ms were identified using a custom MATLAB program, Speech Pause Analysis (SPA)*; PPT= total pause duration/total passage duration ×100

Phonatory Max F0 (Hz) ‘high pitch’ phonation of /a/ Participants raised their pitch from a normal level to the highest pitch possible while vocalizing /a/, and held the high pitch for 5 seconds. Multi-dimensional Voice Profile (MDVP, Model 5105) software was used to measure the maximum pitch obtained during the sustained vowel.

Resonatory Nasalance (%) Sentence repetition ‘Buy Bobby a puppy’ KAYPentax, Model 6400 nasometer was used to measure nasalance during sentence production.

Articulatory Max velocity (mm/s) of UL_LL Sentence repetition ‘Buy Bobby a puppy’ 3D optical motion capture system (Motion Analysis Corp.) tracked movement of reflective markers on each participant’s face; maximum velocity of relative movement between the upper and lower lips was calculated using SMASH (38)
DDK rate (syll/sec) Repeat/ta/as quickly and clearly as possible on one breath DDK rate = # syllable repetitions/total duration (seconds)
Articulation rate Reading of Bamboo passage Articulation rate = # words produced/total speech duration of passage (excluding pauses > 300ms)

System-level Intelligibility Reading 10 randomly generated sentences (5–15 words in length) from the Speech Intelligibility Test Each participant’s speech sample was transcribed orthographically by one naive listener. Intelligibility = % words correctly identified
Speaking rate (wpm) Speaking rate = # words produced/total duration (min)