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. 2017 Jul 6;114(29):E5930–E5939. doi: 10.1073/pnas.1705206114

Fig. S5.

Fig. S5.

Generation of MML-1 resistant cells. (A) Diagrammatic representation of the generation of MML-1 cells over the period of 10 mo by treating MML-1 cells with increasing doses of vemurafenib (0.2 µM–10 µM). (B) MML-1 parent cells and resistant cells (MML-1R) were treated with vemurafenib (5 µM) to observe the cellular growth at three different time points by microscopy (Scale bars, 10 μm.) (C) Flow cytometry analysis showing the cell cycle arrest at G1/G0 phase. MML-1P, MML-1 parent cells; MML-1R, MML-1 resistant cells. **P < 0.01, ***P < 0.001.