Fig. 5. IC50 values of cisplatin (Pt, white) and flexicates [Fe2 Ln 3]Cl4 (n = 2a–2e) (ΛFe – dark grey, ΔFe – light grey) against (a) MDA-MB-468, (b) HCT116 p53+/+, (c) HCT116 p53–/–, (d) ARPE19 and (e) W138 cells over 96 h; dotted line highlights the relative sensitivity of test compounds compared to cisplatin, (f) in vitro selectivity index (IC50 ARPE19/IC50 HCT116 p53–/–) – broken line at selectivity index = 1 represents no difference in IC50 between tumour and normal cells – note log scale on y axis.
