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. 2017 Jul 19;10:3591–3606. doi: 10.2147/OTT.S139686

Table S2.

The GO BP functional analysis of Module 1

GO BP term Count P-value
GO:0007565~female pregnancy 5 5.01E–06
GO:0042493~response to drug 6 3.85E–05
GO:0006366~transcription from RNA polymerase II promoter 7 3.88E–05
GO:0045944~positive regulation of transcription from RNA polymerase II promoter 8 1.78E–04
GO:1902895~positive regulation of pri-miRNA transcription from RNA polymerase II promoter 3 3.07E–04
GO:0045893~positive regulation of transcription, DNA-templated 6 4.55E–04
GO:0051090~regulation of sequence-specific DNA binding transcription factor activity 3 4.83E–04
GO:0043065~positive regulation of apoptotic process 5 5.67E–04
GO:0032570~response to progesterone 3 0.0012
GO:0007568~aging 4 0.0013
GO:0006954~inflammatory response 5 0.0014
GO:0008285~negative regulation of cell proliferation 5 0.0016
GO:0051591~response to cAMP 3 0.0016
GO:0042127~regulation of cell proliferation 4 0.0017
GO:0034097~response to cytokine 3 0.0021
GO:0061614~pri-miRNA transcription from RNA polymerase II promoter 2 0.0026
GO:0009612~response to mechanical stimulus 3 0.0027
GO:0048661~positive regulation of smooth muscle cell proliferation 3 0.0028
GO:0006950~response to stress 3 0.0029
GO:0060395~SMAD protein signal transduction 3 0.0030
GO:2000144~positive regulation of DNA-templated transcription, initiation 2 0.0091
GO:0009629~response to gravity 2 0.0104
GO:0008283~cell proliferation 4 0.0116
GO:0000733~DNA strand renaturation 2 0.0117
GO:0070365~hepatocyte differentiation 2 0.0130
GO:0032496~response to lipopolysaccharide 3 0.0193
GO:0035994~response to muscle stretch 2 0.0208
GO:0006940~regulation of smooth muscle contraction 2 0.0208
GO:0044849~estrous cycle 2 0.0221
GO:0030224~monocyte differentiation 2 0.0221
GO:0038095~Fc-epsilon receptor signaling pathway 3 0.0225
GO:0031668~cellular response to extracellular stimulus 2 0.0233
GO:0051412~response to corticosterone 2 0.0233
GO:0001701~in utero embryonic development 3 0.0246
GO:0045892~negative regulation of transcription, DNA-templated 4 0.0264
GO:0045987~positive regulation of smooth muscle contraction 2 0.0272
GO:0007186~G-protein coupled receptor signaling pathway 5 0.0276
GO:0010165~response to X-ray 2 0.0284
GO:0032967~positive regulation of collagen biosynthetic process 2 0.0297
GO:0045648~positive regulation of erythrocyte differentiation 2 0.0310
GO:0042981~regulation of apoptotic process 3 0.0313
GO:0021983~pituitary gland development 2 0.0361
GO:0006915~apoptotic process 4 0.0366
GO:2000379~positive regulation of reactive oxygen species metabolic process 2 0.0386
GO:0046677~response to antibiotic 2 0.0411
GO:0070555~response to interleukin-1 2 0.0424
GO:0010634~positive regulation of epithelial cell migration 2 0.0424
GO:0030501~positive regulation of bone mineralization 2 0.0449
GO:0045786~negative regulation of cell cycle 2 0.0474

Note: Count refers to the number of DEGs enriched in the GO BP term.

Abbreviations: BP, biological process; DEGs, differentially expressed genes; GO, Gene Ontology.