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. 2017 Jul 10;11(7):7447–7456. doi: 10.1021/acsnano.7b03859

Figure 4.

Figure 4

(a) Mannose-modified HNPs were composed of NIPAm (63.5 mol %), TBAm (28 mol %), AAc (5 mol %), BIS (2 mol %), and p-acrylamidophenyl-α-d-mannopyranoside (Man, 1.5 mol %). The lectin concanavalin A (ConA, purple) binds specifically to Man sugar units (green) in the mannose-modified HNPs. (b) Δ%RNP frequency distribution histograms obtained from the SPRI adsorption measurements of mannose-modified HNPs alone (transparent blue bars) and mannose-modified HNPs in the presence of 500 nM ConA (solid red bars). Δ%RNP frequency distribution histograms are also plotted for additional SPRI adsorption measurements of mixtures of mannose-modified HNPs and 500 nM ConA in the presence of (c) 1 mM mannose (solid green bars) and (d) 10 mM mannose (solid orange bars). The Δ%RNP frequency distribution histogram for mannose-modified HNPs alone is replotted in (c) and (d) for comparison.