Generation of OWO double emulsion droplets. Forming OWO double emulsions requires two serial junctions like the WOW system, except that the wettability pattern must be flipped so that the first junction is hydrophilic and the second hydrophobic, (a). This leads to generation of OW droplets in the first junction that are encapsulated into monodisperse OWO double emulsions in the second junction, (b), which exhibit narrow inner and outer droplet diameter distributions, (c).