Table 2.
Group | p-value | ||||
---|---|---|---|---|---|
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HCS (N = 21) | MCI (N = 15) | ||||
|
|
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Mean | SD | Mean | SD | ||
Metabolite levels | |||||
GABA (AU) | 1.71 | 0.50 | 1.37 | 0.37 | 0.034 |
Glx (AU) | 16.27 | 2.67 | 14.27 | 1.58 | 0.014 |
NAA (AU) | 7.80 | 0.91 | 7.18 | 0.81 | 0.045 |
Group comparisons were performed by t test statistics.
GABA, Glx, and NAA levels were corrected for CSF, WM, and atrophy. Significant p-values are indicated in bold letters (p < 0.05).
Key: AU, arbitrary units; CSF, cerebrospinal fluid; GABA, γ-aminobutyric acid; Glx, glutamate + glutamine; HCS, healthy control subjects; MCI, mild cognitive impairment; NAA, N-acetyl-aspartate; SD, standard deviation; WM, white matter.