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. Author manuscript; available in PMC: 2017 Jul 27.
Published in final edited form as: J Biomed Mater Res A. 2017 Feb 1;105(4):1195–1207. doi: 10.1002/jbm.a.35978

FIGURE 1.

FIGURE 1

Summary of the key characteristics of MSCs. MSCs ability to modulate the innate immune response, regulate bone turnover, and directly regenerate bone make them ideal candidates for the development of cell-based therapies for aseptic loosening and other conditions were bone loss is due to chronic inflammation.