Table 4.
Risk of Non-cardia Gastric Cancer by Fruit Intake and H. pylori and CagA Status, or Combined Omp and HP 0305 Status in the H. pylori Biomarker Cohort Consortium
| H. pylori status | Fruit Intake | n, cases/controls | OR (95% CI) |
|---|---|---|---|
| H. pylori positive and CagA positive | ≤50th percentile | 454/496 | 1 |
| >50th percentile | 294/406 | 0.82 (0.66–1.03) | |
| H. pylori positive and CagA negative | ≤50th percentile | 19/35 | 0.56 (0.30–1.03) |
| >50th percentile | 14/36 | 0.44 (0.23–0.85) | |
| H. pylori negative | ≤50th percentile | 18/90 | 0.22 (0.13–0.38) |
| >50th percentile | 11/97 | 0.12 (0.06–0.25) | |
| Omp positive and HP 0305 positive | ≤50th percentile | 340/307 | 1 |
| >50th percentile | 213/243 | 0.79 (0.61–1.02) | |
| Omp negative and/or HP 0305 negative | ≤50th percentile | 151/314 | 0.45 (0.34–0.58) |
| >50th percentile | 106/296 | 0.34 (0.26–0.46) |
Abbreviations: CI, confidence interval; OR, odds ratio.
Conditional logistic regression with cases and controls matched on sex, age, and date of biological collection, adjusted for total energy intake, vegetable intake, and smoking status.