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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Xenobiotica. 2016 Apr 21;47(3):245–254. doi: 10.1080/00498254.2016.1174793

Table 1.

[14C]-radioactivity in selected tissues and excreta following a single BEH-TEBP administration (72 h post dose).

Dose recovered 0.1 μmol/kg (Mouse, oral) 0.1 μmol/kg (Rat, oral) 10 μmol/kg (Rat, oral) 0.1 μmol/kg (Rat, IV)
Feces % 92 ± 7 98 ± 8 98 ± 1 77 ± 4
Urine % 3 ± 2 0.3 ± 0.03 0.3 ± 0.04 1.3 ± 0.2
Adipose % 0.1 ± 0.03 0.01 ± 0.01 0.03 ± 0.01 2 ± 0.4
(pmol-eq/g) (2 ± 1) (0.04 ± 0.1) (28 ± 10) (15 ± 3)
Adrenal % 0.01 ± 0.004 0.002 ± 0.002 0.004 ± 0.002 1 ± 0.1
(pmol-eq/g) (18 ± 6) (7 ± 5) (1314 ± 451) (2207 ± 1246)
Blood % 0.02 ± 0.01 0.4 ± 0.4 0.1 ± 0.1 1 ± 0.3
(pmol-eq/g) (0.02 ± 0.01) (0.2 ± 0.2) (3 ± 5) (0.4 ± 0.1)
Brain % 0.01 ± 0.01 0.0002 ± 0.0004 0.001 ± 0.001 0.04 ± 0.02
(pmol-eq/g) (1 ± 1) (0.02 ± 0.05) (13 ± 14) (5 ± 2)
Kidney % 0.01 ± 0.01 0.001 ± 0.001 0.002 ± 0.002 0.2 ± 0.03
(pmol-eq/g) (1 ± 1) (0.1 ± 0.1) (21 ± 32) (22 ± 4)
Liver % 0.3 ± 0.1 0.2 ± 0.2 0.4 ± 0.1 7 ± 1
(pmol-eq/g) (11 ± 0.4) (4 ± 5) (873 ± 328) (144 ± 21)
Lung % 0.01 ± 0.01 0.001 ± 0.001 0.002 ± 0.0004 0.1 ± 0.02
(pmol-eq/g) (2 ± 2) (0.1 ± 0.2) (29 ± 4) (20 ± 5)
Muscle % 0.1 ± 0.1 0.1 ± 0.2 0.1 ± 0.1 5 ± 1
(pmol-eq/g) (0.4 ± 0.3) (0.2 ± 0.4) (10 ± 14) (10 ± 2)
Skin % 0.001 ± 0.002 0.01 ± 0.01 0.04 ± 0.02 3 ± 0.4
(pmol-eq/g) (0.01 ± 0.02) (0.04 ± 0.1) (24 ± 13) (17 ± 3)