Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jan 1;37(7):2555–2566. doi: 10.1177/0271678X16671147

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2016

PMC Copyright notice

Figure 3. — Role of vitamin D3 (VitD3), its receptor (VDR), and osteopontin (OPN) in neurological function and BBB disruption. (a) Pre- and Post-treatment of VitD3 (30 ng/kg) decreased brain water content at 24 (n = 8 per group) and (b) decreased brain water content in Pre-SAH + VD3 group at 72 (n = 6 per group) h after SAH. Pre-SAH + VitD3, intranasal treatment 30 ng/kg/day VitD3 24 h before SAH; Post-SAH + VitD3, intranasal treatment 30 ng/kg/day VitD3 1 h after SAH. ^*P < 0.05 vs. sham. ^#P < 0.05 vs. SAH. (c) Neurobehavioral tests. siRNA, small interfering ribonucleic acid; ^‡P < 0.01 vs. Pre-SAH + VitD3 + Vehicle; ^†P < 0.05 vs. Pre-SAH + VitD3 + Control siRNA; n = 5-6 per group; ^♠P = 0.054 vs. Pre-SAH + VitD3 + Control siRNA. (d) Evans blue extravasation. n = 5 per group.