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. 2017 Jul 27;12(7):e0180616. doi: 10.1371/journal.pone.0180616

Fig 1. Heat map showing upregulated and downregulated differentially expressed genes (DEGs) in irinotecan-resistant colon cancer cells.

Fig 1

A bidirectional hierarchical clustering heat map Constructed using multiExperimental Viewer(MEV). The expression values are log2 fold changes (>1 or <−1, FDR <0.05)) between corresponding irinotecan-resistant HCT116 cell lines and parental HCT116 cell lines. Black represents no change in expression, green represents downregulation, and red represents upregulation.