Table 3. Univariate and Multivariablee analysis: Predictive factors for PICU stay in 368 children admitted for severe imported malaria in mainland France, 1996–2005.
| Variables | No PICU* stay (n = 328) | PICU stay | Univariate analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|---|---|
| (n = 40) | ||||||||
| N (%) | N (%) | OR | IC-95% | P | Adjusted OR | IC-95% | P | |
| Sex | 0.21 | 0.07 | ||||||
| Male | 154 (47.0) | 23 (57.5) | 1.0 | 1.0 | ||||
| Female | 174 (53.0) | 17 (42.5) | 0.7 | 0.3–1.3 | 0.5 | 0.3–1.0 | ||
| Epidemiological strata | 0.18 | 0.03 | ||||||
| Sahelian | 104 (31.7) | 19 (47.5) | 4.3 | 1.0–19.2 | 6.6 | 1.4–31.7 | ||
| and Sub-desert | ||||||||
| Tropical | 108 (32.9) | 12 (30.0) | 2.6 | 0.6–12.1 | 3.0 | 0.6–14.5 | ||
| Equatorial | 47 (14.3) | 2 (5.0) | 1.0 | 1.0 | ||||
| Austral** | 69 (21.0) | 7 (17.5) | 2.4 | 0.5–12.0 | 2.6 | 0.5–13.6 | ||
| Chemoprophylaxis | 0.06 | 0.04 | ||||||
| Adapted and regular | 41 (12.5) | 3 (7.5) | 1.0 | 1.0 | ||||
| Inadequate or irregular | 205 (62.5) | 20 (50.0) | 1.3 | 0.4–4.7 | 1.2 | 0.3–4.4 | ||
| No treatment | 82 (25.0) | 17 (43.6) | 2.8 | 0.8–10.2 | 3.0 | 0.8–11.4 | ||
| Platelet count (x 10^3/mm^3) | 0.002 | 0.001 | ||||||
| ≥ 150 | 103 (31.4) | 6 (15.0) | 1.0 | 1.0 | ||||
| 100–150 | 88 (26.8) | 5 (12.5) | 1.0 | 0.3–3.3 | 0.9 | 0.3–3.2 | ||
| < 100 | 137 (41.8) | 29 (72.5) | 3.6 | 1.4–9.1 | 4.0 | 1.6–10.4 | ||
*: PICU = admission to a pediatric intensive care unit
**: Comoros Islands and Madagascar