Table 1. RNA-seq based marker sets created and used in this study to estimate immune cell levels in tumors.
| Signature | Membership | Description |
|---|---|---|
| TCD8 | CD8A, CD8B | CD8+ T cell |
| Treg | FOXP3, CCR8 | Regulatory T cell |
| Tcell | CD3D, CD3E, CD2 | T cell (general) |
| Bcell | CD19, CD79A, MS4A1 | B cell |
| NK | KIR2DL1, KIR2DL3, KIR2DL4, KIR3DL1, KIR3DL2, KIR3DL3, KIR2DS4 | Natural killer cell |
| Mono | CD86, CSF1R, C3AR1 | Monocyte |
| MFm2 | CD163, VSIG4, MS4A4A | M2 Macrophage |
| TregCD8 | Treg, TCD8 | Treg versus CD8+ T cell |
| NKCD8 | NK, TCD8 | NK versus CD8+ T cell |