Table 2. Associations of loss of CDKN2A with estimates of immune cell types in tumors.
| Signature | Bladder | Breast | Head Neck | Kidney Clear | Lung Adeno | Melanoma | Pancreatic |
|---|---|---|---|---|---|---|---|
| Bcell | -0.38 (2.6) | -0.34 (2) | -0.62 (12) | -0.4 (2) | -0.88 (22.4) | -0.94 (7.2) | |
| MFm2 | -0.35 (2.3) | -0.58 (1.5) | |||||
| Mono | -0.35 (2.6) | -0.34 (1.6) | -0.59 (1.7) | ||||
| NK | -0.38 (4.7) | ||||||
| NKCD8 | 0.5 (6) | ||||||
| TCD8 | -0.63 (12.5) | -0.76 (16.3) | -0.72 (3.3) | ||||
| Tcell | -0.48 (7.9) | -0.76 (19) | -0.65 (3) | ||||
| Treg | -0.58 (12.2) | 0.76 (5.9) | -0.58 (10.3) | -0.58 (1.9) | |||
| TregCD8 | 0.37 (3.1) | 0.74 (4.7) |
Values are reported as Effect Size with associated P values in parenthesis (-log10 P). The units of effect size are change in signature score (units of standard deviation) per unit of GISTIC (log2) CNA change.