Table 7. Association of FGFR3 mutations with estimates of immune cell types across TCGA.
Variant | Signature | Bladder | Head and Neck |
---|---|---|---|
FGFR3 mutant | Bcell | -0.71 (5.3) | |
FGFR3 mutant | MFm2 | -1.09 (15.7) | |
FGFR3 mutant | Mono | -1 (12.5) | |
FGFR3 mutant | Tcell | -0.51 (1.8) | |
FGFR3 mutant | Treg | -0.72 (6.9) | |
FGFR3 G382R | NK | 4.61 (5) | |
FGFR3 S249C | MFm2 | -0.86 (1.9) |
Values are reported as Effect Size with associated P values in parenthesis (-log10 P). The units of effect size are change in signature score (units of standard deviation) for mutant versus wild type.