Fig 4. Vitamin D receptor (VDR) increases over time following E. coli infection of the uroeptithelium.
C57BL/6 mice were infected with uropathogenic E. coli CFT073 for 14 (A), 24 (B) and 48 hours (C). Staining for VDR protein shows a time-dependent upregulation with initial patchy staining and progressive accumulation. Section without primary antibody is shown as control (D). Bladder lumen is marked with *. Four mice for each time-point.