Table 4.

Neurological symptoms at primary presentation in 37 HIV-infected individuals with CM and after 4 months and 3 years after CM

Category, parameter	Disease presentation (n=37)	4-month follow-up (n=16)	3-year follow-up (n=21)
Neurological symptoms
Cognitive deficits	15 (41)	1 (6)	1 (5)
Coordination disturbance	7 (19)	2 (12)	0 (0)
Speech disturbance	3 (8)	2 (12)	0 (0)
Visual impairment	5 (13)	1 (6)	0 (0)
Facial palsy	1 (3)	0 (0)	0 (0)
Limb paresis	4 (11)	2 (12)	0 (0)
Sensory affection	0 (0)	0 (0)	0 (0)
Seizures	4 (11)	0 (0)	0 (0)
Need help in everyday life	2 (5)	3 (19)	0 (0)
Headache	27 (73)	7 (44)	0 (0)
Fever	29 (78)	2 (12)	0 (0)
Nausea and vomiting	16 (43)	4 (25)	0 (0)
Neck stiffness	12 (32)	0 (0)	0 (0)
Photophobia	3 (8)	0 (0)	0 (0)
Papilledema	2 (5)	0 (0)	0 (0)
Status at follow-up
Progression of neurological symptoms	–	2 (12)	0 (0)
Unchanged neurological symptoms	–	1 (6)	0 (0)
Improvement of neurological symptoms	–	13 (81)	1 (5)
Return to pre-CM level of activity	–	10 (62)	18 (86)

Note: Data presented as n (%) of individuals.

Abbreviation: CM, cryptococcal meningitis.