Table 1:
Compound name | Protein target | Concentration | Supplier | Catalog number |
---|---|---|---|---|
Nerve growth factor | TrkA | 100 ng/µl | BD Biosciences | 356004 |
740YPDGFR | PI3K activator | 50 µg/ml | Tocris Bioscience | 1983 |
LY294002 | PI3K inhibitor | 10 µM | Tocris Bioscience | 1130 |
Wortmannin | PI3K inhibitor | 10 µM | Enzo Life Sciences | BML-ST415 |
PI-103 | PI3K C1 α inhibitor | 50 nM | Echelon Biosciences | B0303 |
IC87114 | PI3K C1 δ inhibitor | 5 µM | Echelon Biosciences | B0305 |
AS605240 | PI3K C1 γ | 25 nM | Echelon Biosciences | B0301 |
Y-27632 | ROCK inhibitor | 5 μM | Cayman Chemical | 10005583 |
Akt1/2 kinase IH | Akt 1/2 inhibitor | 500 nM | Sigma-Aldrich | A6730-5MG |
U0126 | MEK inhibitor | 10 μM | Cayman Chemical | 70970 |
U73122 | PLC inhibitor | 10 μM | Enzo Life Sciences | BML-ST391 |
Chelerythrine | PKC inhibitor | 10 μM | Sigma-Aldrich | 0C020953 2-1 MG |
PP2 | cSrc inhibitor | 500 nM | EMD Millipore | 529573-1 MG |
DADLE | δR-agonist | 10 μM | Tocris | 3790 |