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. 2017 Aug 1;28(16):2202–2219. doi: 10.1091/mbc.E17-01-0030

Table 1:

Pharmacological compounds used throughout the article.

Compound name Protein target Concentration Supplier Catalog number
Nerve growth factor TrkA 100 ng/µl BD Biosciences 356004
740YPDGFR PI3K activator 50 µg/ml Tocris Bioscience 1983
LY294002 PI3K inhibitor 10 µM Tocris Bioscience 1130
Wortmannin PI3K inhibitor 10 µM Enzo Life Sciences BML-ST415
PI-103 PI3K C1 α inhibitor 50 nM Echelon Biosciences B0303
IC87114 PI3K C1 δ inhibitor 5 µM Echelon Biosciences B0305
AS605240 PI3K C1 γ 25 nM Echelon Biosciences B0301
Y-27632 ROCK inhibitor 5 μM Cayman Chemical 10005583
Akt1/2 kinase IH Akt 1/2 inhibitor 500 nM Sigma-Aldrich A6730-5MG
U0126 MEK inhibitor 10 μM Cayman Chemical 70970
U73122 PLC inhibitor 10 μM Enzo Life Sciences BML-ST391
Chelerythrine PKC inhibitor 10 μM Sigma-Aldrich 0C020953 2-1 MG
PP2 cSrc inhibitor 500 nM EMD Millipore 529573-1 MG
DADLE δR-agonist 10 μM Tocris 3790