Skip to main content
. Author manuscript; available in PMC: 2017 Sep 27.
Published in final edited form as: Oncogene. 2017 Mar 27;36(30):4299–4310. doi: 10.1038/onc.2017.64

Figure 2. Skp2 ablation prevents distal metastasis and prolonged overall survival of TRAMP mice.

Figure 2

(a–c), Representative images and histopathological analysis of adrenal (a), liver (b) and lung (c) organs from TRAMP/Skp2−/− and TRAMP mice of 9–10 months old are presented. Histopathological images are shown with magnification of 10X and 40X. Arrow indicates metastatic adrenal tumor formation and M indicates metastasis. Smaller arrows indicate lung metastasis. (d) Kaplan-Meier plot analysis of cumulative survival rate of TRAMP/Skp2−/−, TRAMP and WT mice.