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. 2017 Jul 27;7:6743. doi: 10.1038/s41598-017-06331-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of SMF on OPC proliferation. (a) Representative images of OPC stained with O4 and Ki67 markers, (b) Quantification of Ki67 positive cells in SMF stimulated OPCs and control, (c) mRNA expression level of proliferative marker Ki67 in SMF stimulated OPCs as compared to control OPCs. Data represented as mean ± SEM. Scale bar = 20 µm.