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. 2017 Jul 27;7:6703. doi: 10.1038/s41598-017-06949-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Antibody recovery by the microfluidic cell retention device. (a) Antibody concentrations from the bioreactor and outer outlet (the permeate stream) of the device were compared daily. Error bars, data range (n = 3, technical replicates). (b) The recovery efficiency close to 100% demonstrates that the microfluidic cell retention device does not suffer from the low product recovery, compared with the membrane-based filtration technologies.