Table 2. Initial RNS results for MuSK MG and DSN MG patients.
MuSK MG (n=45) | DSN MG (n=29) | p | |
---|---|---|---|
Abnormal responses | |||
ADM | 4 (8.9) | 11 (37.9) | 0.002 |
FCU | 7 (15.6) | 16 (55.2) | <0.001 |
TR | 17 (37.8) | 14 (48.3) | 0.372 |
OO | 27 (60.0) | 16 (55.2) | 0.681 |
NA | 29 (64.4) | 17 (58.6) | 0.614 |
Any muscle | 39 (86.7) | 21 (72.4) | 0.126 |
Limb (FCU or ADM) | 10 (22.2) | 17 (58.6) | 0.001 |
Face (NA or OO) | 35 (77.8) | 19 (65.5) | 0.246 |
Pattern of abnormal RNS responses | |||
Abnormal in both limbs and face | 8 (17.8) | 15 (51.7) | 0.002 |
Abnormal only in face | 27 (60.0) | 4 (13.8) | <0.001 |
Abnormal only in limbs | 2 (4.4) | 2 (6.9) | 0.642 |
Normal in both limbs and face | 8 (17.8) | 8 (27.6) | 0.317 |
CMAP decrement (%) | |||
ADM | −2.35±6.44 | −15.03±19.36 | 0.002 |
FCU | −3.67±8.54 | −24.35±30.74 | 0.001 |
TR | −11.53±14.56 | −15.49±17.15 | 0.289 |
OO | −16.74±16.51 | −19.82±25.97 | 0.531 |
NA | −16.37±12.96 | −23.46±23.78 | 0.149 |
Data are n (%) or mean±standard deviation values.
ADM: abductor digiti minimi, CMAP: compound muscle action potential, DSN: double-seronegative, FCU: flexor carpi ulnaris, MG: myasthenia gravis, MuSK: muscle-specific tyrosine kinase, NA: nasalis, OO: orbicularis oculi, RNS: repetitive nerve stimulation, TR: trapezius.