Table 7.
Bonferroni correction for differentially expressed genes (DEGs) enriched functionalities.
| Category | Term | Number of DEGs | Bonferroni |
|---|---|---|---|
| Downregulated DESEQ2 | |||
| GOTERM_BP_FAT | Ribosome biogenesis | 12 | 3.90E−08 |
| GOTERM_BP_FAT | rRNA processing | 10 | 5.80E−08 |
| GOTERM_BP_FAT | rRNA metabolic process | 10 | 5.80E−08 |
| GOTERM_BP_FAT | Ribonucleoprotein complex biogenesis | 12 | 5.10E−07 |
| GOTERM_BP_FAT | ncRNA processing | 12 | 8.30E−07 |
| GOTERM_BP_FAT | ncRNA metabolic process | 12 | 3.40E−05 |
| GOTERM_BP_FAT | RNA processing | 14 | 1.20E−03 |
| GOTERM_CC_FAT | Nucleolus | 11 | 2.00E−07 |
| GOTERM_CC_FAT | Small nucleolar ribonucleoprotein complex | 4 | 1.90E−03 |
| GOTERM_CC_FAT | Ribonucleoprotein complex | 13 | 2.00E−03 |
| GOTERM_CC_FAT | Nuclear lumen | 12 | 9.40E−03 |
| GOTERM_CC_FAT | Eukaryotic transl. initiation factor 3 complex | 4 | 8.00E−03 |
| GOTERM_MF_FAT | RNA binding | 14 | 1.40E−02 |
| SP_PIR_KEYWORDS | RNA-binding | 10 | 1.80E−03 |
| SP_PIR_KEYWORDS | Ribosome biogenesis | 5 | 4.70E−03 |
| SP_PIR_KEYWORDS | rRNA processing | 5 | 4.00E−03 |
| Upregulated DESEQ2 | |||
| GOTERM_BP_FAT | Amine biosynthetic process | 6 | 8.80E−03 |
| GOTERM_BP_FAT | Cellular amino acid biosynthetic process | 5 | 8.50E−03 |
| GOTERM_BP_FAT | Carboxylic acid biosynthetic process | 5 | 9.90E−02 |
| GOTERM_BP_FAT | Organic acid biosynthetic process | 5 | 9.90E−02 |
Categories: GOTERM_BP_FAT, biological process; GOTERM_CC_FAT, cellular component; GOTERM_MF_FAT, molecular function.
SMART & INTERPRO, protein domains; SPIR_KEYWORD, protein information resource provided by SWISSPROT and UniProt.