Table 1.
Comparison of the patient characteristics
| Variables | CVD-ILD group | IIPs group | p value* |
|---|---|---|---|
| Total number of patients | 16 | 70 | |
| Age (years) | 66.5 (16)** | 73.0 (11.3)** | 0.132 |
| Gender | 0.0201 | ||
| Male | 6 (37.5%) | 62 (88.6%) | |
| Female | 10 (62.5%) | 8 (11.4%) | |
| Brinkman index | 600 (900)** | 1000 (1000)** | 0.0057 |
| Number of comorbidities | 0.119 | ||
| 1 | 0 | 8 (11.4%) | |
| 2 | 10 (62.5%) | 31 (44.3%) | |
| 3 | 6 (37.5%) | 19 (27.2%) | |
| 4≤ | 0 | 12 (17.1%) | |
| ILD pattern on CT | 0.0709 | ||
| UIP pattern | 10 (62.5%) | 58 (82.9%) | |
| NSIP pattern | 6 (37.5%) | 12 (17.1%) | |
| %VC | 109.7 (40.4)** | 108.7 (34.5)** | 0.893 |
| %DLco | 57.4 (16.1)** | 55.5 (27.6)** | 0.478 |
| KL-6 (U/mL) | 481 (342.5)** | 514 (440)** | 0.699 |
| Neoadjuvant chemotherapy | 0 | 2 (2.9) | 0.494 |
| Pathology | 0.614 | ||
| Adenocarcinoma | 9 (56.3%) | 30 (42.9%) | |
| Squamous cell carcinoma | 5 (31.2%) | 30 (42.9%) | |
| Others | 2 (12.5%) | 10 (14.2%) | |
| Pathological stage | 0.153 | ||
| I | 9 (56.2%) | 40 (57.1%) | |
| II | 4 (25%) | 11 (15.7%) | |
| III | 2 (12.5%) | 19 (27.2%) | |
| IV | 1 (6.3%) | 0 | |
| Median follow-up (months) | 34 (42.8)** | 30.5 (35.5)** | 0.89 |
*p values were calculated by Fisher’s exact test or the Chi-square test for categorical data, or Mann–Whitney’s U test for continuous data
**Continuous variables are expressed as the median and interquartile ranges which are expressed in parenthesis, and categorical variables are expressed as numbers and percentages (%). CVD-ILD indicates collagen vascular disease-associated interstitial lung disease
IIPs idiopathic interstitial pneumonias, ILD interstitial lung disease, CT computed tomography, UIP usual interstitial pneumonia, NSIP non-specific interstitial pneumonia, VC vital capacity, DL CO carbon monoxide diffusion capacity, KL-6 Krebs von den Lungen-6