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. Author manuscript; available in PMC: 2017 Jul 28.
Published in final edited form as: Lancet Oncol. 2016 Jul 23;17(9):1272–1282. doi: 10.1016/S1470-2045(16)30166-8

Table 1. Baseline characteristics.

Cohort 1 (n=26) Cohort 2 (n=25)
Sex
 Male 15 (58%) 13 (52%)
 Female 11 (42%) 12 (48%)

Race
 White 24 (92%) 20 (80%)
 Other 2 (8%) 5 (20%)

Ethnic origin
 Hispanic or Latino 4 (15%) 3 (12%)
 Other 22 (85%) 22 (88%)

Age (years) 67 (55–74) 65 (58–71)
 <65 12 (46%) 12 (48%)
 ≥65 14 (54%) 13 (52%)

Local recurrent or unresectable cancer 3 (12%) 2 (8%)

Metastatic cancer 23 (88%) 23 (92%)

ECOG performance score
 0 15 (58%) 13 (52%)
 1 11 (42%) 12 (48%)

Previous treatments
 0 19 (73%) 0
 1 4 (15%) 7 (28%)
 2 2 (8%) 9 (36%)
 ≥3 1 (4%) 9 (36%)

Data are number of patients (%) or median (IQR). Cohort 1 includes patients who had not previously received a multikinase inhibitor and cohort 2 includes those previously treated with a multikinase inhibitor. ECOG=Eastern Cooperative Oncology Group.

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