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Morphological changes of leading processes of migrating neurons. (a) Cortical projection neurons extend a leading process and form a cytoplasmic “dilation” at the proximal region of a leading process, and the nucleus in the locomoting neurons becomes elongated to enter the cytoplasmic dilation; (b) Cortical interneurons extend a leading process, a cytoplasmic swelling is formed at the relatively distal region of the process and subsequently the nucleus enters the cytoplasmic swelling.
