Table 1. Characterization Data for BASP-ORCAs and Control Compounds.
composition |
diameter |
relaxivity |
|||||
---|---|---|---|---|---|---|---|
name | m | N | Dh/nm | DTEM/nm | r1/mM–1 s–1 | r2/mM–1 s–1 | notes |
3-CPa | 0.15 | 0.17 | |||||
chex-MMb | 0.21 | 0.30 | |||||
chex-dendrimera | 0.44 | 0.86 | |||||
chex-bottlebrushb | 55.55 | 17b | n.d. | 0.32 | 0.82 | ||
BASP-ORCA | 5.05 | 20 | 31 ± 2 | n.d. | 0.27 | 6.92 | poor solubility (<10 mg/mL) |
BASP-ORCA | 5.05 | 30 | 49 ± 6 | n.d. | 0.53 | 7.11 | poor solubility (<10 mg/mL) |
BASP-ORCA1 | 7.07 | 20 | 31 ± 4 | 37 ± 7 | 0.41 | 4.67 | good solubility (>50 mg/mL) |
BASP-ORCA | 7.07 | 30 | 36 ± 3 | n.d. | 0.35 | 7.40 | poor solubility (<10 mg/mL) |
BASP-ORCA | 9.99 | 15 | 28 ± 3 | 38 ± 10 | 0.33 | 2.90 | low relaxivity |
BASP-ORCA | 9.99 | 30 | 33 ± 4 | 39 ± 10 | 0.37 | 4.52 | low relaxivity |