Table 1.
Subject Demographics, TCD, Macroscopic and Histopathology Findings
| Variable | Asymptomatic | Symptomatic | p-value | |
|---|---|---|---|---|
| N | 23 | 37 | ||
|
| ||||
| Gender, women n (%) | 9 (39.13) | 13 (35.14) | ||
|
| ||||
| Age mean (SD) | 68 (6.73) | 69.11 (11.46) | ||
|
| ||||
| Transcranial Doppler | ||||
| HITS Present n (%) | 5 (21.7) | 10 (27) | 0.88 | |
|
| ||||
| Macroscopic | Asymptomatic | Symptomatic | p-value | |
| n (%) | n (%) | |||
| Ulceration Rating | 0.964 | |||
| 1 | 1 (5) | 4 (11) | ||
| 2 | 2 (10) | 3 (8) | ||
| 3 | 8 (38) | 8 (22) | ||
| 4 | 10 (48) | 22 (59) | ||
| Cholesterol Rating | 0.381 | |||
| 1 | 2 (10) | 2 (5) | ||
| 2 | 9 (43) | 15 (41) | ||
| 3 | 8 (38) | 13 (35) | ||
| 4 | 2 (10) | 7 (10) | ||
| Calcification Rating | 0.931 | |||
| 1 | 6 (29) | 6 (16) | ||
| 2 | 3 (14) | 8 (22) | ||
| 3 | 1 (5) | 9 (24) | ||
| 4 | 11 (52) | 14 (38) | ||
| Thrombus Rating | 0.141 | |||
| 1 | 11 (52) | 14 (38) | ||
| 2 | 8 (38) | 13 (35) | ||
| 3 | 0 (0) | 2 (5) | ||
| 4 | 2 (10) | 8 (22) | ||
|
| ||||
| Histopathology | Asymptomatic | Symptomatic | p-value | |
|
| ||||
| Hemosiderin | n (%) | n (%) | 0.913 | |
| 0 | 13 (65) | 20 (61) | ||
| 1 | 3(15) | 9 (27) | ||
| 2 | 4 (20) | 2 (6) | ||
| 3 | 0 (0) | 2 (6) | ||
| Inflammation | 0.549 | |||
| 0 | 3 (15) | 3 (9) | ||
| 1 | 12 (60) | 18 (55) | ||
| 2 | 2 (10) | 8 (24) | ||
| 3 | 3 (15) | 4 (12) | ||
| Percent Cholesterol | 0.369 | |||
| Mean (SD) | 53.25 (25.77) | 58.94 (20.34) | ||
| Range | 10–90 | 20–90 | ||
| Percent Calcium | 0.109 | |||
| Mean (SD) | 26.00 (22.22) | 17.27 (16.06) | ||
| Range | 0–65 | 0–60 | ||
| Percent hemorrhage | 0.169 | |||
| Mean (SD) | 2.25 (2.55) | 6.06 (11.51) | ||
| Range | 0–5 | 0–60 | ||