Table 2.

Diagnostic accuracies of genotype classification by RMD and SPRT assessed by computer simulations

Fetal DNA fraction, %	No. of positive droplets	Call rate, %*	Accuracy, %†
5	200	0.7	84.8
	400	6.5	93.5
	600	16.1	93.2
	800	24.4	95.4
	1000	33.5	94.8
	1200	40.3	96.0
	1400	47.3	95.9
	1600	52.1	96.2
	1800	57.2	96.7
	2000	60.7	97.1
10	200	28.8	93.6
	400	56.9	95.8
	600	72.2	97.2
	800	80.0	98.1
	1000	86.9	98.6
	1200	90.8	99.0
	1400	93.5	99.4
	1600	95.6	99.5
	1800	96.5	99.6
	2000	97.5	99.8
15	200	60.9	96.9
	400	85.1	98.5
	600	93.2	99.4
	800	97.4	99.7
	1000	98.3	99.9
	1200	99.4	99.9
	1400	99.7	100.0
	1600	99.9	100.0
	1800	100.0	100.0
	2000	100.0	100.0
20	200	84.1	98.2
	400	96.4	99.7
	600	99.2	99.9
	800	99.8	100.0
	1000	99.9	100.0
	1200	100.0	100.0
	1400	100.0	100.0
	1600	100.0	100.0
	1800	100.0	100.0
	2000	100.0	100.0
30	200	98.6	99.8
	400	100.0	100.0
	600	100.0	100.0
	800	100.0	100.0
	1000	100.0	100.0
	1200	100.0	100.0
	1400	100.0	100.0
	1600	100.0	100.0
	1800	100.0	100.0
	2000	100.0	100.0

^*Call rate (%) corresponds to the percentage of samples that achieves the SPRT threshold to make a call.

^†Accuracy (%) refers to the percentage of samples showing a correct call.