Table 3.

Multiple Regression Analysis Models for Explaining the Variance of Diastolic Parameters Among Individuals With Metabolic Syndrome

Variable	β	B±SE	P Value	R 2 Change
2C LA Vol
CSA	0.621	0.0002±0.000	0.11	0.196
Wall thickness	0.718	0.017±0.006	0.02	0.377
Wall:lumen ratio	0.605	0.014±0.005	0.02	0.347
Endothelial function	0.210	0.002±0.004	0.57	0.040
Endo l‐NMMA	0.001	0.0002±0.004	1.00	0.000
hsCRP	0.023	0.001±0.007	0.94	0.001
TNF	0.300	0.009±0.012	0.49	0.062
IL‐6	0.127	0.003±0.010	0.789	0.009
Lateral E:E′
CSA	0.206	0.0001±0.000	0.60	0.023
Wall thickness	0.495	0.017±0.010	0.11	0.195
Wall:lumen ratio	0.596	0.019±0.007	0.02	0.352
Endothelial function	0.088	0.001±0.005	0.80	0.007
Endo l‐NMMA	0.143	0.003±0.005	0.59	0.017
hsCRP	−0.026	−0.001±0.010	0.93	0.001
TNF	−0.527	−0.020±0.012	0.12	0.239
IL‐6	−0.868	−0.024±0.009	0.03	0.429
E:A ratio
CSA	0.291	−0.00001±0.000	0.14	0.046
Wall thickness	0.119	0.002±0.003	0.48	0.011
Wall:lumen ratio	−0.045	−0.001±0.003	0.77	0.002
Endothelial function	0.010	0.0001±0.002	0.96	0.000
Endo l‐NMMA	−0.092	−0.001±0.002	0.64	0.007
hsCRP	0.011	0.000±0.003	0.94	0.000
TNF	−0.096	−0.002±0.004	0.57	0.008
IL‐6	−0.018	0.000±0.004	0.93	0.000

Multiple regression analysis is shown using left atrial volume, E:A ratio, lateral E:E′ as outcome variables and cross‐sectional area, wall thickness, wall‐to‐lumen ratio, endothelial function, endothelial function in presence of l‐NMMA, highly sensitive CRP, TNF, and IL‐6 as explanatory variables. Correlations were adjusted for age and sex. B±SE represents unstandardized coefficients (coefficients of the estimated regression model). β represents standardized coefficients. R ² represents coefficient of variations. Values are mean±SD. CSA indicates cross‐sectional area; IL‐6, interleukin 6; 2C LA Vol, 2‐chamber left atrial volume; hsCRP, highly sensitive C‐reactive protein; l‐NMMA, N ^G‐monomethyl‐l‐arginine; TNF, tumor necrosis factor.