Figure 2.

Serum IL‐34 level predicted poor outcomes in heart failure, especially in those with renal dysfunction. A, Kaplan–Meier curves for the primary end point of 4 groups divided using the median IL‐34 level and an eGFR=60 mL/min per 1.73 m² as the cut‐off values: non‐CKD with IL‐34 below the median, non‐CKD with IL‐34 above the median, CKD with IL‐34 below the median, and CKD with IL‐34 above the median. Log‐rank tests were used to compare the impact of IL‐34 on patients with or without CKD. B, Kaplan–Meier curves for the primary end point according to 4 groups divided using the median IL‐34 and median cystatin C level as the cut‐off values, similar to that illustrated in (A). Log‐rank tests were also performed. CKD indicates chronic kidney disease; CysC, cystatin C; eGFR, estimated glomerular filtration rate; IL, interleukin.