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. 2017 Mar 24;6(4):e005257. doi: 10.1161/JAHA.116.005257

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© 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Geometric mean N‐terminal pro–B‐type natriuretic peptide (NT‐proBNP) vs body mass index (BMI; A‐C), systolic blood pressure (SBP; D‐F), and estimated glomerular filtration rate (eGFR; G‐I) by genotype at rs198389 at visit 2 (average age 57), visit 4 (average age 63), and visit 5 (average age 76). The histogram represents the distribution of the variable on the x axis and the lines represent spline smoothed mean values of NT‐proBNP within rs198389 genotypes at each x axis variable level. P value for test of equality between rs198389 genotypes. Adjusted for age, sex, and race; SBP adjusted for +15 mm Hg if taking antihypertension medications.