Table 3.
Biophysical Properties of Sodium Channels in HEK293 Cells Coexpressing SCN5A and Either VCL‐WT or Empty Vector
| Samples | Peak I Na | Activation | Inactivation | |||||
|---|---|---|---|---|---|---|---|---|
| pA/pF | n | V1/2 (mV) | k | n | V1/2 (mV) | k | n | |
| SCN5A+VCL | −145±8 | 13 | −41.5±0.9 | 5.0 | 13 | −84.4±1.5 | 5.1 | 13 |
| SCN5A+empty vector | −113±10a | 13 | −41.2±0.8 | 5.0 | 13 | −85.1±1.2 | 5.1 | 13 |
Values are mean±SE for n experiments. I Na indicates sodium current; k, slope factor; pA/pF, current density; V1/2, voltage of half‐maximal activation/inactivation; VCL, vinculin; WT, wild type.
a
P=0.02 vs SCN5A+VCL.