Table 1.
Baseline and Procedural Characteristics
| Baseline and Procedural Characteristics | All Patients (N=709) |
|---|---|
| Demographic characteristics | |
| Age, median, y (IQR) | 84 (79–87) |
| Female, n (%) | 300 (42.3) |
| Socioeconomic status (%) | |
| 1st Quintile (lowest) | 124 (17.5) |
| 2nd Quintile | 135 (19.0) |
| 3rd Quintile | 138 (19.5) |
| 4th Quintile | 149 (21.0) |
| 5th Quintile (highest) | 159 (22.4) |
| Missing | SC |
| Cardiac history (%) | |
| Past myocardial infarction | 224 (31.6) |
| Ischemic heart disease | 514 (72.5) |
| History of heart failure | 632 (89.1) |
| Heart failure hospitalization within 90 days | 127 (17.9) |
| New York Heart Association Class | |
| I and II | 107 (15.1) |
| III and IV | 474 (66.8) |
| Missing | 128 (18.1) |
| Left ventricular ejection fraction | |
| ≤50% | 183 (25.8) |
| >50% | 514 (72.5) |
| Missing | 12 (1.7) |
| Past cardiac surgery, n (%) | |
| Coronary artery bypass grafting | 244 (34.4) |
| Aortic valve replacement | 65 (9.2) |
| Mitral valve replacement or repair | 16 (2.3) |
| Tricuspid valve replacement or repair | SC |
| History of percutaneous coronary intervention | 247 (34.8) |
| History of implantable cardiac defibrillator | 12 (1.7) |
| History of permanent pacemaker | 87 (12.3) |
| Atrial fibrillation/flutter | 228 (32.2) |
| Comorbid noncardiac conditions (%) | |
| Diabetes mellitus | 326 (46.0) |
| Hypertension | 678 (95.6) |
| Hyperlipidemia | 510 (71.9) |
| Peripheral vascular disease | 90 (12.7) |
| Cerebrovascular disease | 126 (17.8) |
| Chronic obstructive pulmonary disease | 104 (14.7) |
| History of cancer | 55 (7.8) |
| Cognitive impairment/dementia | 12 (1.7) |
| Dialysis | 23 (3.2) |
| Frailty | 138 (19.5) |
| Preprocedural blood work (%) | |
| Serum creatinine | |
| <120 μmol/L | 486 (68.5) |
| 120 to 200 μmol/L | 143 (20.2) |
| ≥200 μmol/L | 31 (4.4) |
| Missing | 49 (6.9) |
| Hemoglobin status | |
| Anemiaa | 448 (63.2) |
| Missing | 68 (9.6) |
| Preprocedural echocardiographic parameters | |
| Mean transvalvular gradient, mean (SD), mm Hgb | 46 (15) |
| Preprocedural risk score | |
| Society of Thoracic Surgeons score, mean (SD), %c | 13 (12) |
| Procedural characteristics (%) | |
| Year of transfemoral aortic valve replacement | |
| 2007 | 9 (1.3) |
| 2008 | 11 (1.6) |
| 2009 | 39 (5.5) |
| 2010 | 72 (10.2) |
| 2011 | 132 (18.6) |
| 2012 | 147 (20.7) |
| 2013 | 228 (32.2) |
| 2014 | 71 (10.0) |
| Prosthesis type | |
| Edwards Sapien | 312 (44.0) |
| Corevalve | 368 (51.9) |
| Missing | 24 (3.4) |
| Other | SC |
| Valve‐in‐valve | 33 (4.7) |
SC indicates small cell, in which patient numbers ≤5 and cannot be released because of privacy regulations; IQR, interquartile range.
a
Men <140 g/L and female <120 g/L.
b
n=90 (12.5%) missing.
c
n=458 (64.6%) missing.