Table 3.
Performance of ESS for differentiating neoplastic from non-neoplastic polyps based on size
| Sensitivity, % (95% CI) | Specificity, % (95% CI) | Accuracy, % (95% CI) | NPV, % (95% CI) | HCR % (95% CI) | ||
|---|---|---|---|---|---|---|
| All Polyps (N = 218) | High-Confidence Decisions | 91.5 (83.2–96.5) | 92.2 (85.6–96.4) | 91.9 (87.1–95.3) | 93.8 (87.7–97.5) | 90.4 (85.7–93.9) |
| All Decisions | 89.4 (80.8–95.0) | 86.5 (79.5–91.8) | 87.6 (82.5–91.7) | 92.7 (86.7–96.2) | ||
| Polyps < 1 cm (n = 179) | High-Confidence Decisions | 87.0 (73.7–95.1) | 92.1 (85.5–96.3) | 90.6 (85.0–94.7) | 94.6 (88.6–98.0) | 89.3 (83.9–93.5) |
| All Decisions | 83.3 (69.8–92.5) | 86.3 (79.2–91.6) | 85.5 (79.4–90.3) | 93.4 (87.4–97.1) | ||
| Polyps ≤ 5 mm (n = 157) | High-Confidence Decisions | 86.8 (71.9–95.6) | 91.3 (84.1–95.9) | 90.1 (83.9–94.7) | 95.0 (89.5–98.5) | 89.8 (84.0–94.1) |
| All Decisions | 82.5 (67.2–92.7) | 86.3 (78.7–92.0) | 85.3 (78.8–90.5) | 93.5 (87.1–97.4) | ||
| Rectosigmoid Polyps ≤ 5 mm (n = 85) | High-Confidence Decisions | 88.9 (51.8–99.7) | 91.2 (81.8–96.7) | 90.9 (82.2–96.3) | 98.4 (91.5–99.9) | 90.6 (82.3–95.8) |
| All Decisions | 80.0 (44.4–97.5) | 86.7 (76.8–93.4) | 85.9 (76.6–92.5) | 97.0 (86.9–99.6) | ||